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Home»Analysis»Billionaire Stanley Druckenmiller Bets $517,000,000 on One Asset, Increasing Exposure to Largest Holding
Analysis

Billionaire Stanley Druckenmiller Bets $517,000,000 on One Asset, Increasing Exposure to Largest Holding

2025-12-15No Comments2 Mins Read
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Billionaire Stanley Druckenmiller is increasing his asset manager’s exposure to a bet on the future of American health care.

Druckenmiller’s Duquesne Family Office has sold its interest in Natera Inc. (NTRA) increased by 4.19% in the third quarter of 2025.

The company now owns 3,214,532 shares, worth $517.4 million.

The position represents 12.74% of the $4.06 billion portfolio, making it the largest holding.

The increase added 129,342 shares, as reported in the company’s latest 13F-HR submit with the SEC for the quarter ended September 30, 2025.

Druckenmiller initially bought the stock when Natera was trading sideways from late 2022 to early 2023.

He added shares during an ensuing rally, took profits in the first and second quarters of 2025, then bought the dip last quarter.

Natera specializes in non-invasive cell-free DNA testing for oncology, women’s health and organ health.

The company reported 34.66% year-over-year revenue growth in the third quarter of 2025, surpassing analyst estimates. The stock is up more than 500% since its October 2023 low.

A number of analysts predict that Natera’s earnings per share will turn positive by 2028, with double-digit revenue growth expected over the next decade.

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Asset bets Billionaire Druckenmiller Exposure Holding Increasing Largest Stanley
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